eISSN: 2345-6558

Free Access

Journal of Parathyroid Disease 2016;4(1):25-30
Vitamin D and chronic kidney disease
 


Review

Fatemeh Hayati 1, Mohammad Amin Nasouti 1 * , Shokhouh Shayanpour 1, Shahla Ahmadi Halili 1, Hossain Karimpourian 1, Zarrin Beladi Mousavi 2

1 Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
2 Clinical Supervisor, Ferideh Behbehani Hospital, Behbehan Faculty of Medical Sciences, Behbehan, Iran


*Corresponding author: Mohammad Amin Nasouti,
Email: moam790@dr.com


Abstract
Prevalence of hypovitaminosis D is increasing in the world especially among poor countries and it has many varieties of manifestation and disease including rickets in children and osteomalacia and osteoporosis in adult. It also can affect on functional of some organ like renal and cardiovascular system and even has effect on mortality rate of some of these patients. Inadequate vitamin D in food regimen is one of reasons of hypovitaminosis D. The production of active form of this vitamin mainly is located in kidney cells, therefore end-stage renal disease (ESRD) patients or patients who have chronic kidney disease (CKD), have high chance for low serum level of the active form of this vitamin. Secondary hyperparathyroidism and renal osteodystrophy which are important side effect of CKD, be happen because of deficiency and defect in absorption of this vitamin. According to rapid increase in the prevalence of hypovitaminosis D, the aim of this review article is to summarize some of investigation about hypovitaminosis D especially among patients who have CKD.
 


Notes

Implication for health policy/practice/research/medical education


Vitamin D deficiency is an important public health problem
because the low level of vitamin D in the blood is a risk
factor for some severe diseases, such as cancer, heart disease,
fractures and falls etc. Vitamin D is also an important factor
in the prevention and treatment of some skeletal and nonskeletal
diseases. Skeletal diseases include rickets in children,
osteoporosis, osteomalacia (known with bone pain) and
bone loss in people with hyperparathyroidism. Non-skeletal
diseases include high blood pressure and high cholesterol,
diabetes, obesity, rheumatoid arthritis, multiple sclerosis,
premenstrual syndrome (PMS), autoimmune diseases
and cancers. Because there are many obstacles to sunshine
exposure, including usage of sunscreen, hats, and other skin
covers, decreased hours of sun exposure during aging and
the winter; therefore, we can see a prompt increase in the
number of people with vitamin D deficiency.

Please cite this paper as: Borji S, Rafieian-Kopaei M. Vitamin D and its importance on public health. J Parathyr Dis. 2016;4(1):20-24.​

 
 

Comments
First name  
Last name  
Email address  
Comments  
Security code



Article
PDF


Export citation
EndNote
Reference Manager
BibTeX
Medlars
Refworks

Cite by
Google Scholar

Google Scholar
Articles by Fatemeh Hayati
Articles by Mohammad Amin Nasouti
Articles by Shokhouh Shayanpour
Articles by Shahla Ahmadi Halili
Articles by Hossain Karimpourian
Articles by Zarrin Beladi Mousavi
Similar articles
Related articles

PubMed
Articles by Fatemeh Hayati
Articles by Mohammad Amin Nasouti
Articles by Shokhouh Shayanpour
Articles by Shahla Ahmadi Halili
Articles by Hossain Karimpourian
Articles by Zarrin Beladi Mousavi


Article Access Statistics
Viewed
PDF Downloaded
Comments

Share this article!
Creative Commons Attribution 4.0 License This work is licensed under a Creative Commons Attribution 4.0 License.
Copyright © 2016 The Author(s)
Published by Nickan Research Institute