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Journal of Parathyroid Disease 2017;5(2):38-41 doi: 10.15171/jpd.2017.03
Crippling bone deformities and a palpable neck lump; rare presentation of a giant parathyroid adenoma

Case Report

Zain Ul Abideen 1, Adnan Arif 2, Abdullah Abbasi 3, Chaudhary Muhammad Junaid Nazar 4 * , Fizza Aroj Aroj 5

1 Department of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan
2 Department of Surgery, Benazir Bhutto Hospital, Rawalpindi, Pakistan
3 Department of Surgery, Holy Family Hospital, Rawalpindi, Pakistan
4 Department of Nephrology and Renal Transplantation, Shifa International Hospital, Islamabad, Pakistan
5 Department of Medicine, Shifa International Hospital, Islamabad, Pakistan


*Corresponding author: Chaudhary Muhammad Junaid Nazar,
Email: dr.cmjnazar@live.co.uk


Abstract
The most common cause of primary hyperparathyroidism is a solitary parathyroid adenoma. The different manifestations of the disease are due to excess parathyroid hormone (PTH) secretion. “Giant parathyroid adenomas” weigh more than 2 g and are rarely evident in clinical examination. We present a young man who presented with severe bone deformities and a palpable neck lump. After surgery, a giant parathyroid adenoma was removed that weighed 33 g. Adenomas weighing more then 30 g are rare and presentation as a neck lump and severe bone disease has seldom been described. In patients presenting with a palpable neck lump, severe bone disease and renal calculi giant parathyroid adenomas should be considered as a possible culprit.

Notes
Please cite this paper as: Ul Abideen Z, Arif A, Abbasi A, Nazar CMJ. Crippling bone deformities and a palpable neck lump; rare presentation of a giant parathyroid adenoma. J Parathyr Dis. 2017;5(1):28-31.

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Copyright © 2016 The Author(s)
Published by Nickan Research Institute