eISSN: 2345-6558

Free Access

Open Access

Journal of Parathyroid Disease 2017;5(2):42-44 doi: 10.15171/jpd.2017.04
Spontaneous bilateral femoral neck fracture in a man with end-stage renal disease and severe secondary hyperparathyroidism

Case Report

Soraya Doustmohamadian, Majid Foroutan *

1 School of Medicine, Semnan University of Medical Science, Semnan, Iran.

*Corresponding author: Majid Foroutan,
Email: dr_forotan@yahoo.com

Medical treatment is the primary recommended method for in the management of severe secondary hyperparathyroidism (SHPT) in pre-dialysis individuals. This paper reports a case of end-stage renal disease (ESRD) and severe SHPT with pathologic bilateral hip fractures. A 61-year-old man, as a known case of ESRD, with radial osteoporosis and persistent SHPT ( intact PTH >2000 pg/mL) and hypercalcemia with appropriate level of phosphorus and 25(OH) D who did not respond to medical treatment referred to hospital with multiple fractures. The patient referred for subtotal parathyroidectomy. One month after parathyroidectomy, parathyroid hormone (PTH) level significantly diminished from its preoperative values. Serum calcium and phosphorus returned to normal values and muscle weakness progressively improved until the patient became able to walk again. Parathyroidectomy in patients with severe secondary hyperparathyroidism (persistent serum levels of intact PTH>800 pg/mL) is suggested, particularly when is associated with severe hypercalcemia and/or hyperphosphatemia, and progressive and debilitating hyperparathyroidism bone disease, that are refractory and resistant to medical therapy.


Please cite this paper as: Doustmohamadian S, Foroutan M. Spontaneous bilateral femoral neck fracture in a man with end-stage renal disease and severe secondary hyperparathyroidism. J Parathyr Dis. 2017;5(2):42-44. DOI: 10.15171/jpd.2017.04.

Copyright © 2017 The Author(s); Published by Nickan Research Institute. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

First name  
Last name  
Email address  
Security code


Export citation
Reference Manager

Cite by
Google Scholar

Google Scholar
Articles by Soraya Doustmohamadian
Articles by Majid Foroutan
Similar articles
Related articles

Articles by Soraya Doustmohamadian
Articles by Majid Foroutan

Article Access Statistics
PDF Downloaded

Share this article!
Creative Commons Attribution 4.0 License This work is licensed under a Creative Commons Attribution 4.0 License.
Copyright © 2016 The Author(s)
Published by Nickan Research Institute