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J parathyr dis. 2014;2(1): 33-37.
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Parathyroid gland function in dialysis patients

Effat Afaghi 1, Ali Tayyebi 1*, Behzad Einollahi 1

1 Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
*Corresponding author: Ali Tayyebi, tayybi.Ali@gmail.com

Abstract

Parathyroid disorder, is a common consequence of end-stage kidney disease (ESRD) and maintenance dialysis patient. This article, aims to investigate parathyroid disorders consisting symptoms, signs, laboratory findings, prevention and its treatment in dialysis patients. Directory of Open Access Journals (DOAJ), Google Scholar, PubMed, and Web of Science has been searched. Secondary hyperparathyroidism is one of disorders in minerals metabolism in ESRD patients, resulted from calcium reduction in blood due to a decrease in synthesis of active vitamin D, acidosis, and an increase in blood phosphorus, and also 1-alpha-hydroxylase deficiency that can cause bone demineralization as well as renal osteodystrophy with symptoms such as bone pain and fractures, and even vessels and soft-tissue calcification which can affect duration of hospitalization, hospital costs and length and quality of life. The findings show that with accurate measurement of serum level of laboratory values of alkaline phosphatase, calcium, and phosphorous monthly, and parathormone every six months, training the dialysis patients, recommending a diet with low phosphorous and appropriated use of phosphate binding agents will improve the outcome of hemodialysis patients.
Keywords: Parathormone, Hyperparathyroidism, Dialysis, Renal osteodystrophy

Implication for health policy/practice/research/ medical education

Accurate measurement of serum level of laboratory values of alkaline phosphatase, calcium, and phosphorous monthly, and parathormone every six month, training the dialysis patients, recommending a diet with low phosphorous and appropriated use of phosphate binding agents with improve the outcome of hemodialysis patients.  

Please cite this paper as: Afaghi E, Tayyebi A, Einollahi B. Parathyroid gland function in dialysis patients. J Parathyr Dis 2014; 2(1): 33-3

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ePublished: 01 Mar 2014
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