Logo-jpd
J parathyr dis. 2014;2(1): 47-50.
  Abstract View: 404
  PDF Download: 344

Case Report

Normal alkaline phosphatase level in a patient with primary hyperparathyroidism due to parathyroid adenoma

Behzad Einollahi 1, Mehrdad Taghipour 1, Mohsen Motalebi 1, Mahdi Ramezani-Binabaj 2*

1 Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
2 Student Research Committee, Baqiyatallah University of Medical Science, Tehran, Iran
*Corresponding author: Mahdi Ramezani-Binabaj, ramezanimahdi70@gmail.com

Abstract

Primary hyperparathyroidism is relatively an uncommon condition, where the majority of cases present asymptomatically after biochemical testing showing a mild hypercalcemia and elevated parathyroid hormone (PTH) level. Long-standing elevated serum calcium level can lead to renal insufficiency. High serum PTH levels are associated with elevated alkaline phosphatase (ALP) levels in the general population. We present, an 89-year-old woman who initially manifested acute renal failure due to hypercalcemia and, finally, was diagnosed parathyroid adenoma. An interesting issue that drew our attention was the elevation of serum PTH level, despite the normal serum ALP concentration. It is the most important topic in this presentation. According to direct relationship between serums intact PTH and ALP in primary hyperparathyroidism, any failure in increasing levels of ALP, draw our attention to a range of diseases. Differential diagnoses for low ALP activity are mentioned in this case report.
Keywords: Primary hyperparathyroidism, Parathyroid hormone, Alkaline phosphatase

Implication for health policy/practice/research/ medical education

Clinical manifestation of primary hyperparathyroidism has shifted from a symptomatic disease to no specific symptoms ("asymptomatic" primary hyperparathyroidism). However, the most common cause of hypercalcemia is primary hyperparathyroidism and it should be considered in the patients with an elevated serum calcium level.

Please cite this paper as: Einollahi B, Taghipour M, Motalebi M, Ramezani-Binabaj M. Normal alkaline phosphatase level in a patient with primary hyperparathyroidism due to parathyroid adenoma. J Parathyr Dis 2014; 2(1): 47-50.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 404

Your browser does not support the canvas element.


PDF Download: 344

Your browser does not support the canvas element.

ePublished: 01 Mar 2014
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)