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J parathyr dis. 2014;2(2): 78-80.
  Abstract View: 307
  PDF Download: 107

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Correlation of serum parathyroid hormone with pulmonary artery pressure in non-diabetic regular hemodialysis patients

Maryam Heidari 1, Saeed Mardani 1, Azar Baradaran 2*

1 Department of Internal Medicine, Division of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran.
2 Department of Clinical Pathology, Isfahan University of Medical Sciences, Isfahan, Iran.
*Corresponding author: Prof. Azar Baradaran, azarbaradaran@med.mui.ac.ir

Abstract

Introduction: Pulmonary artery hypertension in end-stage renal disease is associated by significantly increased morbidity and mortality. Serum parathormone may increase among patients on hemodialysis and influence various organs.

Objectives: This study sought to find the association of serum parathormone level and pulmonary artery pressure in a group of non-diabetic patients on regular hemodialysis.

Materials and Methods: This prospective investigation was conducted in the hemodialysis section of Shahrekord University of Medical Sciences in 2013. Doppler echocardiography were used to assess pulmonary artery pressure. Pulmonary arterial hypertension is defined as systolic PAP≥35 mm Hg at rest. Serum parathormone was measured by ECL method.

Results: Sixty-five, non-diabetic hemodialysis patients were studied. Mean (±SD) of age of the patients was 56.35±20.41 years. Mean (±SD) of iPTH was 251.55±97.27 pg/ml. In this study, a significant positive association of serum iPTH with pulmonary artery pressure in patients was seen (r=0.27, p=0.029).

Conclusion: In the present study, we detected a significant positive association of serum parathyroid hormone with pulmonary artery pressure of hemodialysis patients however, our observations, warranting further investigations to evaluate the clinical aspect of the association of serum PTH with pulmonary artery pressure.

Keywords: End-stage renal disease, Hemodialysis, Pulmonary hypertension, Parathormone

Implication for health policy/practice/research/ medical education

In the present study, we detected a significant positive association of serum PTH with pulmonary artery pressure of hemodialysis patients however, our observations, warranting further investigations to evaluate the clinical aspect of the association of serum PTH with pulmonary artery pressure.  

Please cite this paper as: Heidari M, Mardani S, Baradaran A. Correlation of serum parathyroid hormone with pulmonary artery pressure in non-diabetic regular hemodialysis patients. J Parathyr Dis 2014; 2(2): 78-80.

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ePublished: 01 Sep 2014
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