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J parathyr dis. 2020;8(1): e04.
  Abstract View: 17
  PDF Download: 6

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An ecological study on distribution of vitamin D level among pregnant women of Iran

Soheila Akbari 1, Faezeh Salehinasab 2, Seyyed Ezatollah Rafiee Alavi 3* ORCID logo

1 Department of Obstetrics and Gynecology, Lorestan University of Medical Sciences, Khorramabad, Iran.
2 Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
3 Department of Pathology, Lorestan University of Medical Sciences, Khorramabad, Iran
*Corresponding author: Seyyed Ezatollah Rafiee Alavi, Email: erafieialavi@gmail.com

Abstract

Introduction: Vitamin D3 is a hormone that acts as immune modulator. Vitamin D deficiency is associated with pregnancy complications such as preeclampsia. Therefore vitamin D deficiency is important in pregnant women.

Objectives: This study is designed to investigate ecological distribution of 25-hydroxy vitamin D (25-OHD) level in the Iranian pregnant women.

Materials and Methods: The present s is an ecological study based on the geographical information presented in previous papers. Ecological map is designed according to northing (X) and easting (Y) of each individual location as well as 25-OHD level as the depth (Z) of the map.

Results: A total of 17 studies were selected from 2005 to 2016. The contour plot showed that eastern and north eastern areas of Iran had higher levels of 25-OHD whereas western and north western areas of Iran showed lower levels of 25-OHD. Around 49.72% of the total area of Iran showed 25-OHD level less than 21.09 ng/mL, 81.91% of the total area showed 25-OHD level less than 25.54 ng/ mL and 96.51% of the total area showed 25-OHD level less than about 29.98 ng/mL.

Conclusion: This ecological study with a novel statistical methodology showed that mean of 25-OHD level in pregnant women was less than about 30 ng/mL in more than 96% of the total area of Iran. Because of the association of vitamin D level with pregnancy complications, surveillance interventions are necessary to change the current status.

Keywords: Vitamin D, Pregnancy complications, ecological study
Please cite this paper as: Akbari S, Salehinasab F, Rafiee Alavi SE. An ecological study on distribution of vitamin D level among pregnant women of Iran. J Parathyr Dis. 2020;8:e04
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Submitted: 15 Aug 2019
Accepted: 27 Dec 2019
ePublished: 07 Jan 2020
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