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J Parathyr Dis. 2013;1(1): 9-11.
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Brief Communication

Impact of diabetes mellitus on parathyroid hormone in hemodialysis patients

Hamid Nasri*

1 Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding Author: *Corresponding author: Prof. Hamid Nasri, , Email: hamidnasri@med.mui.ac.ir

Abstract

Secondary hyperparathyroidism can progress early in the course of chronic kidney disease and becomes more noticeable as renal function declines. We studied the effect of diabetes mellitus on parathyroid function in 60 hemodialysis patients. Serum intact parathormone, calcium, phosphorus and alkaline phosphatase were measured. In this study, serum intact parathormone and alkaline phosphatase were significantly lower among diabetics than non-diabetic hemodialysis patients. We interpreted that a significantly lower parathyroid activity in diabetic hemodialysis patients, implies more prevalence of bone disease in elderly diabetic hemodialysis patients. Further study of bone disease in this group of patients is required to evaluate its effect on outcome and different therapeutic interventions.

 Implication for health policy/practice/research/ medical education

Secondary hyperparathyroidism can progress early in the course of chronic kidney disease and becomes more noticeable as renal function declines. We studied the effect of diabetes mellitus on parathyroid function in 60 hemodialysis patients. Serum intact parathormone, calcium, phosphorus and alkaline phosphatase were measured. In this study, serum intact parathormone and alkaline phosphatase were significantly lower among diabetics than non-diabetic hemodialysis patients. We interpreted that a significantly lower parathyroid activity in diabetic hemodialysis patients, implies more prevalence of bone disease in elderly diabetic hemodialysis patients. Further study of bone disease in this group of patients is required to evaluate its effect on outcome and different therapeutic interventions.

Please cite this paper as: Nasri H. Impact of diabetes mellitus on parathyroid hormone in hemodialysis patients. J Parathyr Dis 2013; 1(1): 9-11.

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ePublished: 24 Feb 2013
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