Marzieh Kafeshani
1, Mahtab Zarafshani
2, Sara Shokri-Moghaddam
2, Ali Ahmadi
3, Hamid Nasri
2*1 Food Security Research Center and Department of Clinical Nutrition/Community Nutrition/Food Science & Technology, School of Nutrition & Food
2 Science, Isfahan University of Medical Sciences, Isfahan, Iran.
3 Nickan Research Institute, Isfahan, Iran.
4 Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Abstract
Introduction: Vitamin D deficiency is a common health problem throughout the world. There is growing interest in vitamin D status as a potentially adjustable risk factor for diabetes mellitus.
Objectives: The main aim of this investigation is to assess, the possible differences of vitamin D serum value of diabetics versus normal persons.
Patients and Methods: This study was a cross-sectional investigation was conducted on 106 persons (females; 44, males; 62) consisting of 75 subjects, were free of any diseases who had normal fasting blood sugar (FBS) and 31 type 2 diabetic patients. Blood level of 25-hydroxy vitamin D [25(OH) D] was FBS, 2-hour postprandial blood sugar (2-h PPBS), calcium, creatinine, and uric acid were measured using standard kits. The independent t test was used to determine the significance of any baseline differences between groups and Pearson correlation test was used to assess correlations by STATA software version 12.
Results: The mean serum 25(OH) D concentration was 27.44± 3.66 and 27.64 ± 5.62 nmol/l in diabetics, and normal persons respectively. There was any significant difference in serum 25-hydroxy vitamin D level between diabetic and normal individuals. The prevalence of vitamin D deficiency (<50 nmol/l) was 88.87% in diabetic and 92% in normal subjects respectively.
Conclusion: The prevalence of vitamin D deficiency was high in two groups, however, there was not any significant difference in serum 25-hydroxy vitamin D level between diabetics and normal individuals.
Implication for health policy/practice/research/medical education
In a cross-sectional investigation on 106 persons consisting
of 75 normal subjects, 31 type 2 diabetic patients, we
found the prevalence of vitamin D deficiency was high in
two groups but there was not any significant difference in
serum 25-hydroxy vitamin D level between diabetic and
normal individuals. However, this finding requires further
investigation.
Please cite this paper as: Kafeshani M, Zarafshani M, Shokri-Moghaddam S, Ahmadi A, Nasri H. Serum 25-hydroxy vitamin D level in diabetic patients versus normal individuals; a pilot study. J Parathyr Dis. 2016;4(2):40-43.
Please cite this paper as: Kafeshani M, Zarafshani M, Shokri-Moghaddam S, Ahmadi A, Nasri H. Serum 25-hydroxy vitamin D level in diabetic patients versus normal individuals; a pilot study. J Parathyr Dis. 2016;4(2):40-43.
Please cite this paper as: Kafeshani M, Zarafshani M, Shokri-Moghaddam S, Ahmadi A, Nasri H. Serum 25-hydroxy vitamin D level in diabetic patients versus normal individuals; a pilot study. J Parathyr Dis. 2016;4(2):40-43.