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J Parathyr Dis. 2021;9: e11159.
  Abstract View: 323
  PDF Download: 154

Epidemiology and Prevention

Human recombinant soluble ACE2 (HrsACE2) application and mechanism of action in coronavirus disease 2019

Alireza Pouramini 1* ORCID logo, Fatemeh Kafi 2 ORCID logo, Sina Bakhshaei 3 ORCID logo, Bina Bakhshaei 4 ORCID logo, Rastina Mehrani 5 ORCID logo, Kamyab Karimpour 2 ORCID logo

1 Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2 Nickan Research Institute, Isfahan, Iran.
3 Internal Medicine Department, UHS SoCal Medical Education Consortium Temecula, Ca, USA.
4 Neurology Department, Median Klinik NRZ, Wiesbaden, Germany.
5 School of Medicine, St George University, Grenada.
*Corresponding Author: *Corresponding author: Alireza Pouramini, Email: , Email: alirezapouraminiarpa@gmail.com

Implication for health policy/practice/research/medical education: A Finding an effective treatment for COVID-19 is essential because of the severe risks it causes to human health. Previous studies have shown that COVID-19 can penetrate cells and initiate its harmful effects on organs via binding to the angiotensin-converting enzyme 2 (ACE2) receptor. According to recent research, the hrsACE2 receptor may form a link with the virus before engaging with the ACE2 receptor on the cell membrane, preventing the subsequent deleterious effects.

Please cite this paper as: Pouramini A, Kafi F, Bakhshaei S, Bakhshaei B, Mehrani R, Karimpour K. Human recombinant soluble ACE2 (HrsACE2) application and mechanism of action in coronavirus disease 2019. J Parathyr Dis. 2021;9:e11159.

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Submitted: 03 Dec 2021
Accepted: 14 Dec 2021
ePublished: 25 Dec 2021
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