J Parathyr Dis. 2022;10: e11161.
doi: 10.34172/jpd.2022.11161
  Abstract View: 1237
  PDF Download: 523


Correlation of thyroid status with severity and mortality of COVID-19 patients

Elahe Zaremoghadam 1 ORCID logo, Ensiye Pordel 2 ORCID logo, Mostafa Assarroudi 3 ORCID logo, Saeid Mohammadi 4 ORCID logo, Ali Kalali Sani 3 ORCID logo, Hossein Mardanparvar 5 ORCID logo, Sara Abbasian 2* ORCID logo

1 Department of Internal Medicine, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
2 Department of Nursing, Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
3 Department of Nursing, Torbat Jam Faculty of Medical Sciences, Torbat Jam, Iran.
4 Student Research Committee, School of Dentistry, Europian University of Georgia, Tibilisi, Georgia.
5 Department of Nursing, Faculty of Nursing and Midwifery, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
*Corresponding Author: Corresponding author: Sara Abbasian, Email: , Email: S.abbasian13@yahoo.com


Introduction: Thyroid status because of the expression of angiotensin-converting enzyme-2 (ACE2), which is a functional receptor for coronavirus disease 2019 (COVID-19) in thyroid glands, maybe affects COVID-19 patients’ outcomes.

Objectives: This study aimed to evaluate the correlation of thyroid status with the severity and mortality of COVID-19 patients.

Patients and Methods: In a retrospective cohort study conducted on 521 COVID-19 patients, data were collected by a demographic questionnaire and a checklist of patient outcomes (death/recovery) from the hospital information system (HIS) and analyzed by SPSS version 26 and binary logistic regression. Data about thyroid status were collected from clinical documents and laboratory test data.

Results: Most patients were male (57.2%) with a mean age of 56.12 ± 17.4 years. Seventy-seven patients had a severe stage of disease, and 55 patients died. Twenty-one patients had hyperthyroidism, and 53 patients had hypothyroidism. Results showed that the correlation between hypothyroidism and hyperthyroidism with severity and mortality risk of COVID-19 patients was insignificant (P > 0.05).

Conclusion: In this study, we concluded that, thyroid status is not associated with COVID-19 outcomes such as severity or mortality.

Please cite this paper as: Zaremoghadam E, Pordel E, Assarroudi M , Mohammadi S, Kalali Sani A, Mardanparvar H, Abbasian S. Correlation of thyroid status with severity and mortality of COVID-19 patients. J Parathyr Dis. 2022;10:e11161. doi: 10.34172/jpd.2022.11161.
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Submitted: 19 Aug 2021
Accepted: 13 Oct 2022
ePublished: 19 Oct 2022
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