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J Parathyr Dis. 2022;10: e11167.
doi: 10.34172/jpd.2022.11167
  Abstract View: 62
  PDF Download: 37

Review

Gender difference in COVID-19 vaccination; recent concepts

Parisa Soleimani 1 ORCID logo, Hamid Reza Jahantigh 2 ORCID logo, Sepideh Yadollahifarsani 1* ORCID logo

1 Nickan Research Institute, Isfahan, Iran.
2 Animal Health and Zoonosis PhD Course, Department of Veterinary Medicine, University of Bari, Bari, Italy.
*Corresponding Author: *Corresponding author: Sepideh Yadollahifarsani, Email: , Email: sepid.y.f@gmail.com

Abstract

Recently, a few different vaccines have been developed to help end the COVID-19 pandemic. These vaccines have made significant progress toward controlling the disease. Multiple factors contribute to the immunity level that these vaccines can stimulate, including sex. The effect of gender on other vaccines’ efficacy has been studied before. The results of these studies are mentioned below. Genetic and hormonal differences between men and women are among the mechanisms suggested for the difference in vaccine efficacy in men and women. Sex hormones play various roles in stimulating or suppressing the immune system. As a result, they are responsible for the intensity and speed at which the vaccine establishes the immune response. In this narrative review study, we discuss the differences in COVID-19 vaccine efficacy and safety between the two genders and the reasons for these differences.

Please cite this paper as: Soleimani P, Jahantigh HR,Yadollahifarsani S. Gender difference in COVID-19 vaccination; recent concepts. J Parathyr Dis. 2022;10:e11167 doi: 10.34172/jpd.2022.11167.
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Submitted: 27 Aug 2022
Accepted: 20 Oct 2022
ePublished: 31 Oct 2022
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