J Parathyr Dis. 2023;11: e11226.
doi: 10.34172/jpd.2023.11226
  Abstract View: 413
  PDF Download: 265


Cinacalcet in patients with primary hyperparathyroidism; a review

Hamid Reza Hemmati* ORCID logo

1 Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran
*Corresponding Author: Hamid Reza Hemmati, Email: dr.hemmati2007@yahoo.com, , Email: dr.hhemmati@semums.ac.ir


Primary hyperparathyroidism (PHPT) is a condition characterized by the parathyroid glands’ overproduction of parathyroid hormone (PTH). These increases calcium levels in the blood, leading to various symptoms and complications. Cinacalcet is a promising therapeutic option for patients with PHPT who are unable or unwilling to undergo surgery. It effectively reduces serum calcium and PTH levels, improving biochemical markers of bone turnover and renal function. However, more research is needed to determine the optimal dosage, duration, and long-term effects of cinacalcet treatment in this patient population. Clinicians should carefully consider the risks and benefits of cinacalcet therapy individually and involve patients in shared decision-making.

Please cite this paper as: Hemmati HR. Cinacalcet in patients with primary hyperparathyroidism; a review. J Parathyr Dis. 2023;11:e11226. doi:10.34172/jpd.2023.11226.
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Abstract View: 414

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PDF Download: 265

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Submitted: 26 May 2023
Accepted: 13 Aug 2023
ePublished: 22 Aug 2023
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