Pregnancy and lactation-associated osteoporosis is a rare form of osteoporosis that occurs during last trimester of pregnancy and lactation, causing bone resorption. This leads to bone fractures especially in the spine and hip. Symptoms are severe low back pain and physical disability and height loss. Pregnancy and lactation–associated osteoporosis occurs in three main forms: Post pregnancy spinal osteoporosis, transient osteoporosis of the hip, heparin induced osteoporosis in pregnancy. The aim of this article is to review the forms of pregnancy and lactation-associated osteoporosis.