Parisa Tajdini
1* 
, Simin Mazaheri Tehrani
2 , Yasaman Vahdani
3* 1 Clinical Research Development Unit, Amir-Al-Momenin Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran.
2 Department of Molecular Biotechnology and Health Sciences, School of Medicine, University of Turin, Turin, Italy.
3 Department of Biochemistry and Molecular Medicine, University of Montreal, Canada.
Abstract
Parathyroid crisis (storm), also known as parathyroid storm, is an extremely rare and life-threatening endocrine emergency caused by excessive secretion of parathyroid hormone (PTH). It is characterized by sudden and severe hypercalcemia, which can lead to multi-organ dysfunction and failure. This review paper aims to provide an in-depth understanding of parathyroid crisis, including its pathophysiology, clinical presentation, diagnosis, and management options.