Administration of cinacalcet in pediatric patients with CKD; a short-review on recent concepts

Sayed Yousef Mojtahedi; Paniz Pourpashang

doi:10.34172/jpd.2025.12269

J Parathyr Dis. 2025;13: e12269.
doi: 10.34172/jpd.2025.12269

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Mini-Review

Administration of cinacalcet in pediatric patients with CKD; a short-review on recent concepts

Sayed Yousef Mojtahedi ¹ , Paniz Pourpashang ¹^*

¹ Pediatric Chronic Kidney Disease Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran

*Corresponding Author: Paniz Pourpashang, Email: paaniz.p@gmail.com

Abstract

Cinacalcet shows promise in treating secondary hyperparathyroidism (sHPT) in both pediatric and adult chronic kidney disease (CKD) populations; however, its efficacy appears more pronounced in adults. Pediatric patients face unique challenges that can hinder treatment success, necessitating careful monitoring and individualized approaches to therapy. Further research is essential to optimize dosing strategies and improve outcomes for children receiving cinacalcet.

Keywords: Cinacalcet, Dialysis, Pediatrics, Chronic kidney disease, Secondary hyperparathyroidism, Hypocalcemia, End-stage kidney disease

Please cite this paper as: Mojtahedi SY, Pourpashang P. Administration of cinacalcet in pediatric patients with CKD; a short-review on recent concepts. J Parathyr Dis. 2025;13:e12269. doi:10.34172/jpd.2025.12269.